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New York City has always been a place where you can make an impression.

That goes for people — and unfortunately — the microbes that carry disease.

“(The city) has been a crossroads of people, goods, ideas and also of germs,” said Sarah Henry, chief curator of the Museum of the City of New York and co-curator of the new exhibit called “Germ City: Microbes and the Metropolis.”

The exhibit, which opens Friday, takes a colorful and interactive look at how infectious disease and epidemic outbreaks have impacted the city over time. It also examines the role of city officials and how government progressed from taking a reactive response to health crises to mounting ambitious efforts to stop them.

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